Symbol
Name
ID

Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
MGI:99614

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

enlarged spleen

decreased spleen weight

abnormal macrophage physiology

increased circulating interferon-gamma level

abnormal type IV hypersensitivity reaction

increased interferon-gamma secretion

increased acute inflammation

increased susceptibility to endotoxin shock

increased inflammatory response

decreased susceptibility to bacterial infection

increased susceptibility to bacterial infection

decreased susceptibility to Retroviridae infection

increased susceptibility to Retroviridae infection

Availability

Mouse Genotype

Mst1r^Fv2-s/Mst1r^Fv2-s

Mst1r^tm1.1Sew/Mst1r^tm1.1Sew

Mst1r^tm1Ber/Mst1r^tm1Ber

Mst1r^{tm2(Mst1r*)Sew}/Mst1r^{tm2(Mst1r*)Sew}

Mst1r^tm1Sjd/Mst1r⁺

Foxa1^tm1(cre)Sew/Foxa1⁺
Mst1r^tm1Sew/Mst1r^tm1Sew (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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